Neurodegenerative Disease Lab

PUBLICATIONS

papers list
29	Ascochlorin suppresses MMP-2-mediated migration and invasion by targeting FAK and JAK-STAT signaling cascades. Cho HJ, Park JH, Nam JH, Chang YC, Park B, Hoe HS. [J Cell Biochem. (2017) ] Abstract
28	A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Suppresses Cell Migration and Invasion in Monomorphic Malignant Human Glioma Cells by Inhibiting FAK/STAT3 Signaling. Nam JH, Cho HJ, Kang H, Lee JY, Jung M, Chang YC, Kim K, Hoe HS. [J Cell Biochem. (2017) ] Abstract
27	Polo-like kinase 2 phosphorylation of amyloid precursor protein regulates activity-dependent amyloidogenic processing. Lee Y, Lee JS, Lee KJ, Turner RS, Hoe HS, Pak DT. [Neuropharmacology. (2017) ] Abstract
26	Delphinidin inhibits angiogenesis through the suppression of HIF-1α and VEGF expression in A549 lung cancer cells. Kim MH, Jeong YJ, Cho HJ, Hoe HS, Park KK, Park YY, Choi YH, Kim CH, Chang HW, Park YJ, Chung IK, Chang YC. [Oncol Rep. (2017) ] Abstract
25	A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway. Song JM, Sung YM, Nam JH, Yoon H, Chung A, Moffat E, Jung M, Pak DT, Kim J, Hoe HS. [J Alzheimers Dis. (2016) ] Abstract
24	Hexa (ethylene glycol) derivative of benzothiazole aniline promotes dendritic spine formation through the RasGRF1-Ras dependent pathway. Lee NJ, Song JM, Cho HJ, Sung YM, Lee T, Chung A, Hong SH, Cifelli JL, Rubinshtein M, Habib LK, Capule CC, Turner RS, Pak DT, Yang J, Hoe HS. [Biochim Biophys Acta. (2016) ] Abstract
23	microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain. Kim J, Yoon H, Horie T, Burchett JM, Restivo JL, Rotllan N, Ramirez CM, Verghese PB, Ihara M, Hoe HS, Esau C, Fernandez-Hernando C, Holtzman DM, Cirrito JR, Ono K, Kim J. [J Neurosci. (2015) ] Abstract
22	Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease. Megill A, Tran T, Eldred K, Lee NJ, Wong PC, Hoe HS, Kirkwood A, Lee HK. [J Neurosci. (2015) ] Abstract
21	Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner. DiBattista AM, Dumanis SB, Song JM, Bu G, Weeber EJ, Rebeck GW, Hoe HS. [BBA Molecular Cell Research. (2015) ] Abstract
20	Deficiency in LRP6-mediated WNT signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer’s disease. Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G. [Neuron. (2014) ] Abstract
19	Extracellular proteolysis of reelin by tissue plasminogen activator following synaptic potentiation. Trotter JH, Lussier AL, Psilos KE, Mahoney HL, Sponaugle AE, Hoe HS, Rebeck GW, Weeber EJ. [Neuroscience. (2014) ] Abstract
18	A tetra(ethylene glycol) derivative of benzothiazole aniline rescues dendritic spine density and cognitive function in a mouse model of Alzheimer’s disease. Song JM, DiBattista AM, Sung YM, Turner RS, Yang J, Pak DTS, Lee HK, Hoe HS. [Experimental Neurology. (2014) ] Abstract
17	Antihypertensive drug Valsartan promotes dendritic spine density by altering AMPA receptor trafficking. Sohn YI, Lee NJ, Chung A, Saavedra JM, Turner RS, Pak DTS, Hoe HS [Biochem Biophys Res Commun. (2013) ] Abstract
16	Soluble ICAM-5, a product of activity dependent proteolysis, increases mEPSC frequency and dendritic expression of GluA1. Lonskaya I, Partridge J, Lalchandani RR, Chung A, Lee T, Vicini S, Hoe HS, Lim ST, Conant K. [Plos One. (2013) ] Abstract
15	A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras mediated spinogenesis Megill A, Lee TH, DiBattista AM, Song JM, Spitzer MH, Rubinshtein M, Habib LK, Capule CC, Mayer M, Turner RS, Kirkwood A, Yang J, Pak DTS, Lee HK, Hoe HS. [J Neurosci. (2013) ] Abstract
14	Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse. Rogers JT, Zhao L, Trotter JH, Rusiana I, Peters MM, Li Q, Donaldson E, Banko JL, Keenoy KE, Rebeck GW, Hoe HS, D’Arcangelo G, Weeber EJ. [J Psychopharmacol. (2013) ] Abstract
13	Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer’s disease. Sung YM, Lee TH, Yoon HJ, DiBattista AM, Song JM, Sohn YJ, Moffat EI, Turner RS, Jung M, Kim J, Hoe HS. [Experimental Neurology. (2012) ] Abstract
12	FE65 as a link between VLDLR and APP to regulate their trafficking and processing. Dumanis SB, Chamberlain KA, Sohn YJ, Lee YJ, Guenette SY, Suzuki T, Mattews PM, Pak DTS, Rebeck GW, Suh YH, Park HS, Hoe HS. [Mol Neurodegener (2012) ] Abstract
11	MiR-106b impairs cholesterol efflux and increases Abeta levels by repressing ABCA1 expression. Kim J, Yoon H, Ramirez CM, Lee SM, Hoe HS, Fernandez-Hernando C, Kim J. [Exp Neurol. (2012) ] Abstract
10	Decreased dendritic spine density and abnormal spine morphology in Fyn knockout mice. Babus LW, Little EM, Keenoy KE, Minami SS, Chen E, Song JM, Caviness J, Koo SY, Pak DT, Rebeck GW, Turner RS, Hoe HS. [Brain Res. (2011) ] Abstract
9	Reelin supplementation enhances cognitive ability, synpatic plasticity, and dendritic spine density. Rogers JT, Rusiana I, Trotter J, Zhao L, Donaldson E, Pak DT, Babus LW, Peters M, Banko JL, Chavis P, Rebeck GW, Hoe HS, Weeber EJ. [Learn Mem. (2011) ] Abstract
8	Plk2 Raps up Ras to subdue synapses. Lee KJ, Hoe HS, Pak DT. [Small GTPases. (2011) ] Abstract
7	ApoE receptor 2 regulates synapse and dendritic spine formation. Dumanis SB, Cha HJ, Song JM, Trotter JH, Spitzer M, Lee JY, Weeber EJ, Turner RS, Pak DT, Rebeck GW, Hoe HS. [PLoS One. (2011) ] Abstract
6	Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines. Lee KJ, Moussa CE, Lee Y, Sung Y, Howell BW, Turner RS, Pak DT, Hoe HS. [Neuroscience. (2010) ] Abstract
5	ApoE mimetic peptide decreases Ab production in vitro and in vivo. Minami SS, Cordova A, Cirrito JR, Tesoriero JA, Davis GC, Dakshanamurthy S, Turner RS, Pak DTS, Rebeck GW, Paige M, Hoe HS. [Mol Neurodegener. (2010) ] Abstract
4	ApoE4 Decreases Spine density and Dendritic Complexity in Cortical Neurons in vivo. Dumanis SB, Tesoriero J, Babus LW, Nguyen M, Trotter J, Ladu M, Weeber EJ, Turner RS, Xu B, Rebeck GW, Hoe HS. [J Neurosci. (2009) ] Abstract
3	The cytoplasmic adaptor protein X11？ and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement. Minami SS, Sung YM, Dumanis SB, Chi SH, Burns MP, Ann EJ, Suzuki T, R. Turner RS, Park HS, Pak DT, Rebeck GW, Hoe HS. [FASEB J. (2009) ] Abstract
2	Novel interaction of Reelin with APP promotes neurite outgrowth. Hoe HS, Lee KJ, Carney RS, Lee JY, Markova A, Lee JY, Howell BW, Hyman BT, Pak DT, Bu G, Rebeck GW. [J Neurosci. (2009) ] Abstract
1	Combinational control of dendritic spine and filopodia morphogenesis by SPAR and alpha-actinin2. Hoe HS, Lee JY, Pak DT. [Biochem Biophys Res Commun. (2009) ] Abstract