Neurogenetics Lab
PUBLICATIONS
| 46 |
PTK2 regulates tau-induced neurotoxicity via phosphorylation of p62 at Ser403 [J Neurogenet. (2022) ] Abstract |
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| 45 |
Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models [Developmental cell (2022) ] Abstract |
| 44 |
Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction [Antioxidants (2021) ] Abstract |
| 43 |
HEXA-018, a Novel Inducer of Autophagy, Rescues TDP-43 Toxicity in Neuronal Cells [Frontiers in Pharmacology (2021) ] Abstract |
| 42 |
Overexpression of SIRT3 Suppresses Oxidative Stress-induced Neurotoxicity and Mitochondrial Dysfunction in Dopaminergic Neuronal Cells [Experimental Neurobiology (2021) ] Abstract |
| 41 |
FUS-induced neurotoxicity is prevented by inhibiting GSK-3β in a drosophila model of amyotrophic lateral sclerosis [Human Molecular Genetics (2021) ] Abstract |
| 40 |
Control of hippocampal prothrombin kringle-2 (pKr-2) expression reduces neurotoxic symptoms in five familial Alzheimer's disease mice [British Journal of Pharmacology (2021) ] Abstract |
| 39 |
Toxicity of pathogenic ataxin-2 in？Drosophila？shows dependence on a pure CAG repeat sequence [Human Molecular Genetics (2021) ] Abstract |
| 38 |
C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons [Human Molecular Genetics (2021) ] Abstract |
| 37 |
Identification of Genetic Modifiers of TDP-43: Inflammatory Activation of Astrocytes for Neuroinflammation [Cells (2021) ] Abstract |
| 36 |
Actin-microtubule crosslinker Pod-1 tunes PAR-1 signaling to control synaptic development and tau-mediated synaptic toxicity [Neurobiol Aging (2020) ] Abstract |
| 35 |
NF-κB disinhibition contributes to dendrite defects in fly models of neurodegenerative diseases. [J Cell Biol. (2020) ] Abstract |
| 34 |
The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B mediated inflammatory response [Journal of Neuroinflammation (2020) ] Abstract |
| 33 |
The Role of Glial Mitochondria in α-Synuclein Toxicity [Front Cell Dev Biol. (2020) ] Abstract |
| 32 |
Recent Advances on the Role of GSK3β in the Pathogenesis of Amyotrophic Lateral Sclerosis [Brain Sci. (2020) ] Abstract |
| 31 |
The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies [Exp Mol Med. (2020) ] Abstract |
| 30 |
The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment [Front Cell Dev Biol. (2020) ] Abstract |
| 29 |
Glutathione S-Transferase Rescues Motor Neuronal Toxicity in Fly Model of Amyotrophic Lateral Sclerosis [Antioxidants (Basel) (2020) ] Abstract |
| 28 |
Induction of GDNF and GFRα-1 Following AAV1-Rheb(S16H) Administration in the Hippocampus in vivo [Exp Neurobiol (2020) ] Abstract |
| 27 |
Behavioral evidence for geomagnetic imprinting and transgenerational inheritance in fruit flies. [Proc Natl Acad Sci U S A. (2020) ] Abstract |
| 26 |
DRG2 Deficient Mice Exhibit Impaired Motor Behaviors with Reduced Striatal Dopamine Release. [Int J Mol Sci. (2019) ] Abstract |
| 25 |
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies [Autophagy (2019) ] Abstract |
| 24 |
Neurotrophic interactions between neurons and astrocytes following AAV1-Rheb(S16H) transduction in the hippocampus in vivo. [Br J Pharmacol. (2019) ] Abstract |
| 23 |
Parkin expression reverses mitochondrial dysfunction in fused in sarcoma-induced amyotrophic lateral sclerosis. [Insect Mol Biol. (2019) ] Abstract |
| 22 |
Effects of Silibinin Against Prothrombin Kringle-2-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System In Vivo. [J Med Food (2019) ] Abstract |
| 21 |
Genetic activation of parkin rescues TAF15-induced neurotoxicity in a Drosophila model of amyotrophic lateral sclerosis. [Neurobiol Aging (2019) ] Abstract |
| 20 |
Inhibition of MEK5 suppresses TDP-43 toxicity via the mTOR-independent activation of the autophagy-lysosome pathway. [Biochem Biophys Res Commun. (2019) ] Abstract |
| 19 |
Dietary Restriction and Neuroinflammation: A Potential Mechanistic Link. [Int. J. Mol. Sci. (2019) ] Abstract |
| 18 |
Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity [Nat Commun. (2018) ] Abstract |
| 17 |
Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo. [Cell Death&Disease (2018) ] Abstract |
| 16 |
Protection of nigral dopaminergic neurons by AAV1 transduction with Rheb(S16H) against neurotoxic inflammation in vivo [Experimental & Molecular Medicine (2018) ] Abstract |
| 15 |
Beneficial Effects of Silibinin Against Kainic Acid-induced Neurotoxicity in the Hippocampus in vivo [Experimental Neurobiology (2017) ] Abstract |
| 14 |
Neuroprotective Effects of Protein Tyrosine Phosphatase 1B Inhibition against ER Stress-Induced Toxicity [Molecules and Cells (2017) ] Abstract |
| 13 |
Mitochondrial chaperone HSP60 regulates antibacterial immunity via p38 MAP kinase signaling [EMBO Journal (2017) ] Abstract |
| 12 |
Deneddylase 1 Regulates Deneddylase Activity of the Cop9 Signalosome in Drosophila Melanogaster. [Insect Scinece. (2017) ] Abstract |
| 11 |
Imbalance of mitochondrial dynamics in Drosophila models of amyotrophic lateral sclerosis [Biochemical and Biophysical Research Communications (2016) ] Abstract |
| 10 |
Protective effect of Drosophila glutathione transferase omega 1 against hydrogen peroxide-induced neuronal toxicity. [Gene. (2015) ] Abstract |
| 9 |
Prion-like Mechanism in Amyotrophic Lateral Sclerosis: are Protein Aggregates the Key? [Experimental Neurobiology. (2015) ] Abstract |
| 8 |
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models. [Nature Genetics. (2014) ] Abstract |
| 7 |
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. [Human Molecular Genetics. (2012) ] Abstract |
| 6 |
A yeast functional screen predicts new candidate ALS disease genes. [PNAS (2011) ] Abstract |
| 5 |
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. [Nature (2010) ] Abstract |
| 4 |
Drosophila Cand1 regulates Cullin3-dependent E3 ligases by affecting the neddylation of Cullin3 and by controlling the stability of Cullin3 and adaptor protein. [Developmental Biology. (2010) ] Abstract |
| 3 |
DEN1 deneddylates non-cullin proteins in vivo. [Journal of Cell Science. (2008) ] Abstract |
| 2 |
The F-actin/microtubule crosslinker Shot is a platform for Krasavietz-mediated translational regulation of midline axon repulsion. [Development. (2007) ] Abstract |
| 1 |
Drosophila homolog of APP-BP1 (dAPP-BP1) interacts antagonistically with APPL during Drosophila development. [Cell Death and Differentiation (2007) ] Abstract |